ADAMTS13 (Human) Recombinant Protein (P01)
产品名称: ADAMTS13 (Human) Recombinant Protein (P01)
英文名称: ADAMTS13 (Human) Recombinant Protein (P01)
产品编号: H00011093-P01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human ADAMTS13 full-length ORF ( AAH39251.1, 1 a.a. - 75 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MQLFGPWGEIVSPSLSPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILVRPSMGTCAVILDSFP
- Theoretical MW (kDa):
- 34.1
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 11093
- GeneBank Accession#:
- BC039251.1
- Protein Accession#:
- AAH39251.1
- Gene Name:
- ADAMTS13
- Gene Alias:
- C9orf8,DKFZp434C2322,FLJ42993,MGC118899,MGC118900,TTP,VWFCP,vWF-CP
- Gene Description:
- ADAM metallopeptidase with thrombospondin type 1 motif, 13
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000022496,OTTHUMP00000022497,OTTHUMP00000022498,a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13,vWF-cleaving protease,von Willebrand factor-cleaving protease
- Related Disease
- Atherosclerosis
- Brain Ischemia
- Cardiovascular Diseases
- Cerebrovascular Accident
- Chronic Disease
- Coronary Disease
- Genetic Predisposition to Disease
- Inflammation
- Myocardial Infarction
- Obesity
- Ovarian Failure, Premature
- Peripheral Vascular Diseases
- Polycystic Ovary Syndrome
- Pregnancy Complications, Hematologic
- Puberty, Delayed
- Puberty, Precocious
- Purpura, Thrombotic Thrombocytopenic
- Stroke
- Thrombophilia